ÍNDICE PLAQUETA-LINFOCITO Y MORTALIDAD INTRAHOSPITALARIA POR ACCIDENTE CEREBROVASCULAR ISQUÉMICO”

Abstract

Ischemic stroke is the second most common cause of mortality worldwide; therefore, it is important to have predictive markers for this outcome. The aim of this study is to evaluate the predictive capacity of the platelet-lymphocyte ratio (PLR) to predict in-hospital mortality in patients with ischemic stroke. A cross-sectional study was conducted with analysis of medical records of patients who experienced their first episode of ischemic stroke. Univariate and multivariate analyses were used, in addition to ROC curve. Of the 293 initial medical records, 140 were included for analysis, the study population has a median age of 63 years (67.1% male). During hospitalization, 28 patients died, representing an in-hospital mortality rate of 20%. A high PLR (>114) in the multivariate model (OR = 6.02; CI 95% = 1.29-28.05, p: 0.022), ICU admission (OR = 15.07; CI 95% = 2.31-98.25, p: 0.005) and NIHSS (OR = 1.18; CI 95% = 1.02-1.34, p: 0.018) was significantly associated with an increased risk of inhospital mortality. The optimal PLR value was 159.4 with a sensitivity of 85.7% and a specificity of 77.7% (p 0.001). Results of this study suggest that a high PLR is significantly associated with an increased risk of in-hospital mortality compared to the group with low PLR, in addition, ICU admission and higher scores on the NIHSS scale are independent variables for mortality.